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The researchers from the CSIR’s Centre for Cellular and Molecular Biology (CCMB) and Institute of Genomics and Integrative Biology sequenced about 64 genomes and located the unique variant referred to as Clade I/A3i.
world
Updated: Jul 30, 2020 08:11 IST
Researchers from the Council of Scientific & Industrial Research (CSIR) try to set up the prevalence of a unique mutation of the SARS-CoV-2 virus that causes Covid-19 that was found in samples of sufferers a pair of months in the past.
The researchers from the CSIR’s Centre for Cellular and Molecular Biology (CCMB) and Institute of Genomics and Integrative Biology sequenced about 64 genomes and located the unique variant referred to as Clade I/A3i. A virus variant is outlined as an isolate (or a set of isolates) whose genomic sequence differs from that of the reference virus. It can be termed as a genetic mutation within the authentic virus.
Hospital-based medical knowledge is getting used to decide the prevalence of Covid-19 infections due to the variant found, and to additionally set up whether or not the mutation discovered is functionally silent or has some virulence. In some instances, mutations of disease-causing viruses causes a decline in virulence, however that’s but to established within the case of this mutation.
“More research is needed to get a prevalence of this particular variant among cases of Covid-19 in India, and also (to find out) how virulent is the strain. It can happen only through analysing data from hospitals. Initially, we picked up 30 odd samples but we would need at least five times more samples,” stated CCMB director Dr Rakesh Mishra. The datasets of Indian SARS-CoV-2 genomes deposited in Global Initiative on Sharing All Influenza Data until May 25 had been used for the evaluation. “What we have managed to sense so far is that this particular variant is dying down and other strains are infecting (people) more but this needs to be scientifically established.”
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