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Using blood plasma from COVID-19 survivors to deal with sufferers with extreme pneumonia brought on by the novel coronavirus confirmed little profit, in response to information launched on Tuesday from a medical trial in Argentina.
The remedy know as convalescent plasma, which delivers antibodies from COVID-19 survivors to contaminated folks, didn’t considerably enhance sufferers’ well being standing or cut back their threat of dying from the illness any higher than a placebo, the research printed in The New England Journal of Medicine discovered.
Despite restricted proof of its efficacy, convalescent plasma, which U.S. President Donald Trump touted in August as a “historic breakthrough,” has been often given to sufferers within the United States.
In October, a small research from India recommended convalescent plasma improved signs in COVID-19 sufferers, akin to shortness of breath and fatigue, however didn’t cut back the danger of dying or development to extreme illness after 28 days.
The new Argentine research concerned 333 hospitalized sufferers with extreme COVID-19 pneumonia who have been randomly assigned to obtain convalescent plasma or a placebo.
After 30 days, researchers discovered no important variations in sufferers’ signs or well being. The mortality fee was almost the identical at 11% within the convalescent plasma group and 11.4% within the placebo group, a distinction not deemed statistically important.
It continues to be potential that convalescent plasma would possibly assist much less-sick COVID-19 sufferers, research chief Dr. Ventura Simonovich of the Hospital Italiano de Buenos Aires stated, however extra research can be wanted and provides of the remedy are usually not scalable.
For sufferers with extreme illness, like those on this research, “other therapies based on antibodies could have a role,” he stated.
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